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Tuesday, October 13, 2026

中大研究揭示「CD8⁺調節性T細胞」成動脈粥樣硬化新型治療靶點

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動脈粥樣硬化可造成冠狀動脈疾病及中風等併發症。中大醫學院最新研究揭示一種名為「CD8⁺調節性T細胞」(簡稱保護性CD8⁺ Treg)的免疫細胞,可作為新型治療靶點對抗動脈粥樣硬化。研究團隊發現「效應CD8⁺ T細胞」會影響血管細胞的正常運作,加速動脈粥樣硬化惡化。他們進一步證實,透過非溶細胞性抗CD8α抗體誘導「保護性CD8⁺ Treg」以恢復血管細胞的Notch訊號,抑制其異常增殖及表型轉換,從而減緩動脈粥樣硬化進程。

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